Logomaker for Antibody CDRs - AbXtract

Category Paths

Follow one of these paths in the Orion user interface, to find the floe.

  • Solution-based/Biologics/Antibody Design

  • Role-based/Bioinformatician

  • Role-based/Biologist

  • Product-based/AbXtract

Description

This floe will produce sequence logos by region of interest (ROI) and output to Floe Report.

Titles of required parameters (promoted names)

  • Processed RECORDS, long-read or single-chain (data_in) type: data_source: The dataset(s) from which to read records.
  • Split by cluster? Only applies to downstream records. (sequence_logo_by_cluster) type: boolean: Indicates whether to split sequences by cluster before creating sequence logos. Cluster logos are output only if not more than 500 records.
    Default: False
  • ROI for sequence logo (choose Chain1 CDR3 if short-read/single-chain data) (sequence_logo_roi) type: string: Name of regions to be aligned for sequence logo. Logo is output only if not more than 500 records.
    Default: CDR3 Chain_2 (Downstream Chain)
    Choices: CDR3 Chain_1 (Upstream Chain), CDR3 Chain_2 (Downstream Chain), HCDR3 and LCDR3

Optional parameters (promoted names)

  • Skip consolidation based on ‘Region of Interest (ROI) for Condensing Sequences’ (skip_clone_consolidation) type: boolean: This will return every clone in a separate row of the resulting CSV file
    Default: False