Renumber and Restyle Antibody

Category Paths

Follow one of these paths in the Orion user interface, to find the floe.

  • Role-based/Computational Chemist

  • Solution-based/Virtual-screening/Target Preparation

  • Solution-based/Hit to Lead/Target Preparation/Structural Data Preparation

  • Solution-based/Biologics/Antibody Design/Target Preparation

  • Task-based/Target Prep & Analysis/Protein Preparation

Description

This floe takes an existing antibody design unit and will renumber the structure into a different naming scheme and apply a style according to the new scheme.

Potential Input Sources: Antibody Experimental Structure Prep Floe, Antibody Sequences to 3D Models Floe

Related Floes: Antibody Surface Patch Generation Floe

Promoted Parameters

Title in user interface (promoted name)

Annotation

Sequence Numbering Scheme (numbering_scheme): This parameter sets the numbering scheme applied to antibodies.

  • Required

  • Type: string

  • Default: IMGT

  • Choices: [‘IMGT’, ‘Chothia’, ‘Martin’, ‘Kabat’]

Style Liabilities (style_liabilities): Option to style known liability patterns.

  • Required

  • Type: boolean

  • Default: True

  • Choices: [True, False]

Remove Existing Surfaces (remove_surf): Option to remove existing surface on the input record.

  • Required

  • Type: boolean

  • Default: False

  • Choices: [True, False]