Renumber and Restyle Antibody¶
Category Paths
Follow one of these paths in the Orion user interface, to find the floe.
Role-based/Computational Chemist
Solution-based/Virtual-screening/Target Preparation
Solution-based/Hit to Lead/Target Preparation/Structural Data Preparation
Solution-based/Biologics/Antibody Design/Target Preparation
Task-based/Target Prep & Analysis/Protein Preparation
Description
This floe takes an existing antibody design unit and will renumber the structure into a different naming scheme and apply a style according to the new scheme.
Potential Input Sources: Antibody Experimental Structure Prep Floe, Antibody Sequences to 3D Models Floe
Related Floes: Antibody Surface Patch Generation Floe
Promoted Parameters
Title in user interface (promoted name)
Annotation
Sequence Numbering Scheme (numbering_scheme): This parameter sets the numbering scheme applied to antibodies.
Required
Type: string
Default: IMGT
Choices: [‘IMGT’, ‘Chothia’, ‘Martin’, ‘Kabat’]
Style Liabilities (style_liabilities): Option to style known liability patterns.
Required
Type: boolean
Default: True
Choices: [True, False]
Remove Existing Surfaces (remove_surf): Option to remove existing surface on the input record.
Required
Type: boolean
Default: False
Choices: [True, False]