Renumber and Restyle Antibody

Category Paths

Follow one of these paths in the Orion user interface, to find the floe.

  • Role-based/Computational Chemist

  • Solution-based/Virtual-screening/Target Preparation

  • Solution-based/Hit to Lead/Target Preparation/Structural Data Preparation

  • Solution-based/Biologics/Antibody Design/Target Preparation

  • Task-based/Target Prep & Analysis/Protein Preparation

Description

This floe takes an existing antibody design unit and will renumber the structure into a different naming scheme and apply a style according to the new scheme.

Potential Input Sources Antibody Sequences to 3D Models, Antibody Experimental Structure Prep

Promoted Parameters

Title in user interface (promoted name)

Annotation

Sequence Numbering Scheme (numbering_scheme): This parameter sets the numbering scheme applied to antibodies.

  • Required

  • Type: string

  • Default: IMGT

  • Choices: [‘IMGT’, ‘Chothia’, ‘Martin’, ‘Kabat’]

Style Liabilities (style_liabilities): Option to style known liability patterns.

  • Required

  • Type: boolean

  • Default: True

  • Choices: [True, False]

Remove Existing Surfaces (remove_surf): Option to remove existing surface on the input record.

  • Required

  • Type: boolean

  • Default: False

  • Choices: [True, False]