Gigadock Collection to Hi-res FastROCS Collection

Category Paths

Follow one of these paths in the Orion user interface, to find the floe.

  • Product-based/FastROCS

  • Role-based/Computational Chemist

  • Solution-based/Virtual-screening/DB Preparation

  • Task-based/Data Science/Conversion

Description

Creates a high resolution FastROCS collection with up to 200 conformers per molecule, as opposed to a max of 10 in a standard FastROCS collection, from an existing Giga Docking collection.

For single query FastROCS runs this collection will likely be x3-x4 more expensive than the standard FastROCS collection of the same molecules. For multi query the cost can increased by up to x20.

Promoted Parameters

Title in user interface (promoted name)

Inputs

Input Giga Docking Collection (molecule_input_collection): The Giga Docking collection to convert into a hires FastROCS collection.

  • Required

  • Type: collection_source

Outputs

Output Hires FastROCS Collection Name (output_hires_fastrocs_collection_name): Name of the collection to create.

  • Required

  • Type: collection_sink

  • Default: Hires FastROCS Collection

Options

Maximum number of conformers per molecule (maximum_number_of_conformers_per_molecule): Molecules with more than this number of conformers will have their conformer count reduced to this value (the highest energy conformers will be deleted).

  • Required

  • Type: integer

  • Default: 200

Development

Molecules Per Shard (molecules_per_shard): Total count on the input shards to accumulate before emitting a group of shards

  • Required

  • Type: integer

  • Default: 100000

Max Number of Convert Cube Instances (max_number_of_convert_cube_instances): The maximum number of concurrently running copies of this Cube

  • Type: integer

  • Default: 1000

Min Shard Download Timeout (min_shard_download_timeout): Minimum timeout for the smart shard to records cubes

  • Required

  • Type: integer

  • Default: 2

Max Shard Download Timeout (max_shard_download_timeout): Maximum timeout for the smart shard to records cubes

  • Required

  • Type: integer

  • Default: 21600.0

Session Retry Dict for Shard Download (session_retry_dict_for_shard_download_): Session retry dict for the smart shard to records cubes

  • Type: string

  • Default: [‘429:1000’, ‘460:1000’, ‘500:1000’, ‘502:1000’, ‘503:1000’, ‘504:1000’]

Shard Download Attempts (shard_download_attempts): Download attempts for the smart shard to records cubes

  • Type: integer

  • Default: 1

Min Shard Upload Timeout (min_shard_upload_timeout): Minimum timeout for the smart records to record shard cubes

  • Required

  • Type: integer

  • Default: 2

Max Shard Upload Timeout (max_shard_upload_timeout): Maximum timeout for the smart records to record shard cubes

  • Required

  • Type: integer

  • Default: 21600.0

Session Retry Dict for Shard Upload (session_retry_dict_for_shard_upload_): Session retry dict for the smart records to record shard cubes

  • Type: string

  • Default: [‘429:1000’, ‘460:1000’, ‘500:1000’, ‘502:1000’, ‘503:1000’, ‘504:1000’]

Shard Upload Attempts (shard_upload_attempts): Download attempts for the smart record to record shard cubes

  • Type: integer

  • Default: 2

Serial Cube Retry Timeout (serial_cube_retry_timeout): Sets the retry timeout (sec) on the cube_session OrionSession for this cube. If unspecified parallel cubes will uses a value of 600 and serial cubes will use a value of 7200.

  • Type: integer

Catch exceptions (catch_exceptions): If Off exception handling will be disabled for this cube.

  • Type: boolean

  • Default: True

  • Choices: [True, False]

Catch exceptions (parallel_catch_exception_methods): Specifies which methods of a parallel cube an exception will be caught and emitted to the exception port if the port is connected. If the exception port is connected to an exception handler this will stop the floe

  • Type: string

  • Default: [‘begin’]

  • Choices: [‘begin’, ‘process’, ‘end’]

Enable cube timing report (time_all_cubes): If true this cube will emit timing information to the timing_data port.

  • Type: boolean

  • Default: True

  • Choices: [True, False]