Protein Modeling Release Notes

v1.1.2 August 2026

General Notice

• This package is built using OpenEye-orionplatform==6.8.0, OpenEye-toolkits==2026.1.0, and OpenEye-Snowball==0.32.0.

Floe Updates

• The Enumerate Pockets on Design Units Floe now promotes site_residue and adds a dedicated Pocket Finding Options parameter group to better control residue-constrained pocket discovery.

v1.1.1 December 2025

General Notice

• This package is built using OpenEye-orionplatform==6.7.0, OpenEye-toolkits==2025.2.1, and OpenEye-Snowball==0.31.1.

v1.0.0 February 2025

General Notice

This is a new package as a part of the Orion Floes reorganization. It includes Floes previously found in the Biomodeler Floes package.

• This package is built using OpenEye-orionplatform==6.3.1, OpenEye-toolkits==2024.2.1, and OpenEye-Snowball==0.29.1.

• The SiteHopper Search Floe has improvements to the GPU prescreen to generate hits with higher accuracy. Options have been added to filter hits based on a sequence similarity cutoff and a patch score cutoff.