OEProteinElectrostatics¶
This namespace contains constants describing handling of protein-ligand electrostatics.
NoElectrostatics
No protein-ligand electrostatic interaction included.
GridPB
Protein electrostatic potential as a solution of PB equation is stored on a grid and used to calculate its electrostatic interaction with any ligand placed inside the protein.
GridCoulomb
Protein Coulomb electrostatic potential is stored on a grid and used to calculate its electrostatic interaction with any ligand placed inside the protein.
ExactCoulomb
Exact Coulombic potential used to calculate protein-ligand electrostatic interaction.
SolventPBForces
Complete PB protein-ligand interaction in solvent is used. Electrostatic protein-ligand interaction is a sum of Coulomb, solvent screening, protein desolvation and ligand desolvation terms.