This is first release of the SiteHopper application suite. SiteHopper can
search a database containing hundreds of thousands of design units for proteins with
similar binding sites to a query design unit in a few minutes using an NVIDIA GPU. SiteHopper can also
create this database from a series of biomolecular structures in
The SiteHopper application suite consists of the following applications:
sitehopper_build generates a database of patches from design units to be searched with sitehopper_search.
sitehopper_search searches a database of design units for proteins with binding sites similar to a query design unit.
A large database of patches based on the public is available for download in a platform-independent format.